Santosa Handojo was born in Indonesia. Santosa Handojo is the majority owner of Japfa Comfeed, which indirectly operates food businesses including a beef manufacturer and chicken processor. In June 2016, U.S. private equity firm KKR bought a 10% stake in subsidiary Japfa Comfeed. In September 2016 Japfa agreed to set up a joint venture with Cargill of the U.S. to produce chicken in Indonesia. Handojo's father was a successful tycoon but most of his original business was wiped out during the 1997 financial crisis.