Sachiko Kuno was born in United States. Japanese scientist with a Ph.D. in biochemical engineering, Sachiko Kuno and her research partner, now husband, Ryuji Ueno, made their fortune as cofounders and majority owners of 2 pharmaceutical firms, Sucampo Pharmaceuticals in Bethesda, Md. and R-Tech Ueno in Japan. The pair moved to the U.S. in 1999. Together they own 2 historic Georgetown mansions, Evermay and Halcyon House. A permanent resident of the U.S., she cofounded and is CEO of S&R Foundation, a nonprofit in Washington D.C. that supports talented individual in the arts, sciences and social entrepreneurship.